axialHealthcare partners with health insurers nationwide to identify and mitigate opioid-related patient risk.

Using integrated technology and targeted clinician engagement, axialHealthcare arms providers with actionable insights to better assess, diagnose, and treat patients for improved outcomes. 


Opioid misuse costs patients, health insurers, and society as a whole.

Study references

[1] Han B, Compton WM, Blanco C, Crane E, Lee J, Jones CM. Prescription Opioid Use, Misuse, and Use Disorders in U.S. Adults: 2015 National Survey on Drug Use and Health. Annals of Internal Medicine [Internet]. 2017 Aug 1.

[2] The Economic Burden of Prescription Opioid Overdose, Abuse, and Dependence in the United States, 2013.Florence CS1, Zhou C, Luo F, Xu L.

[3] Estimating the Costs of Opioid Abuse and Dependence from an Employer Perspective: a Retrospective Analysis Using Administrative Claims Data, 2014.

38% of adults use prescription opioids in a given year[1]

13% of adults prescribed opioids misuse them[1]

17% of adults misusing opioids develop opioid use disorder[1]

$78.5B in aggregate costs for prescription opioid overdose, abuse, and dependence[2]

4x average increase in healthcare costs for patients abusing opioids[3]


Our care solutions are driven by analytics, technology-enabled, and supplemented by ongoing consultation with an expert clinical care team.


Proprietary algorithms monitor patient populations and networks using diverse data sources, including demographic, medical, pharmacy, and behavioral health information.

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Individual patient risk assessment serves as the foundation of comprehensive clinical intelligence delivered to health care providers to inform care.   

We assess patient risk across a range of potential concerns: 

  • Pharmaceutical risk, including dangerous drug combinations, high dose, or multi-prescriber activity
  • Significant health events like an overdose or emergency department visit related to drug use  
  • Predicted risk of a high cost episode or event, such as the likelihood of an opioid overdose or future diagnosis for opioid use disorder (OUD)


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Patient safety should not depend on overburdened providers checking yet another system.

We deliver valuable patient information into the provider workflow via EHR direct message, eFax, secure email, and telephonic outreach from our care team. Information delivery is configurable to individual provider preference and accompanied by patient-specific diagnostic, treatment, and referral support for effective intervention.

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Significant variation in quality exists across provider prescribing patterns and medication-assisted treatment networks.

Our consultative network solution stratifies providers by quality indicators and offers education when warranted, drives member referral strategy, and pinpoints access and quality gaps to support better network decisions. 


Following a year-long partnership, results from a health plan partner are as follows: 

Multi-prescriber activity decreased by 30%

Patients with dangerous polydrug risk dropped 25%

Morphine equivalent daily dose decreased by 25%

Patients on opioid scripts declined by 17%

89% of engaged providers were receptive to the awareness campaign, transparent support, and mission of axialHealthcare

Financial savings for the health plan $1.75 per member per month

“If it wasn’t for BlueCare and programs like axialHealthcare’s, my doors would not still be open. Thank you for your outreach and the resources on the portal.”

– Family Nurse Practitioner, Tennessee

“We really appreciate all the work y’all do for us, and the resources from axialHealthcare have been just wonderful- it’s been so helpful for our office.”

– Nurse, Tennessee

“Thank you. This is so valuable, and I’m glad your company recognizes how important this is and how much we need this vital information. I am so grateful to have access to this, and to your team of pharmacists.”

– CN, Nurse Practitioner, Tennessee

“This program gives access to information that we as primary physicians need to care for our patients. It’s especially useful in a state where opioid over-prescribing is something we’re known for – thanks for these tools and for being available to help.”

– Primary Care Provider, Alabama

“While opioids can be effective in treating acute pain, there is mounting evidence that opioids are less than effective in treating chronic pain—and can actually do more harm than good. Amerigroup has taken an innovative approach to addressing opioid misuse and abuse by engaging axialHealthcare to extend tools and resources to our providers and members that can effectively improve quality of care and enhance health outcomes.”

– Dr. D. Mark Mahler, former Medical Director of Amerigroup TN

“This completely changes the patient’s care.” Referring to Opioid Risk Reports.

– Pain Management Doctor, Alabama